Figure 1. 

A 5-year-old, spayed female, Pit Bull Terrier mix presented with a 2-week history of crusts and worsening skin lesions, mild lethargy, and mildly decreased appetite. Crusting lesions started on the nose and spread to the ears, muzzle, hocks, and all paws, with mucoid green discharge OU. On physical exam, the lesions included crusting, depigmentation, and swelling of the nose/nasal planum. Crusting was noted at the ear base, tips of the pinnae, lateral face, hocks, and on areas on the dorsum. All four paws showed hyperkeratosis on all paw pads, and all paws were swollen. Biopsies were collected prior to initiating any treatments.

Figure 2.

Figure 3.

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Figure 5. H&E, 2x magnification

Figure 6. H&E, 10x magnification.

Figure 7. H&E, 20x magnification

Figure 8. H&E, 20x magnification.

Figure 9. H&E, 40x magnification.